Potassium Acetate in dialysis fluid
One of the most common complications of diabetes is End Stage Renal Disease (ESRD). People whose kidneys no longer function properly need to undergo hemodialysis or peritoneal dialysis for as long as they live, or until they receive a kidney transplant.
Dialysis fluid (dialysate) consists of purified water in which various substances are dissolved. Dialysate regulates the electrolyte and acid-base balance of the dialysis patient and removes waste metabolic products from the body.
Niacet’s pharma acetates, such as sodium acetate, sodium diacetate, magnesium acetate and potassium acetate, play an important role as a buffer regulating the pH level of the dialysis solution. Sodium acetate also enables the liver to produce sodium bicarbonate, which is needed in order to prevent the blood from acidifying.
Sodium acetate is mostly used in solutions. Sodium diacetate is used in dry concentrates and gives better results in the dialysate due to the higher acidity/lower pH. It also better prevents the precipitation of calcium carbonate on the artificial kidney.
Sodium diacetate offers clinics the benefit of being able to locally dissolve the dry mix, instead of having to store a liquid product. Sodium diacetate is also used in other applications where it is advantageous to use a solid source of free acetic acid, e.g. for safer handling and reduced transportation costs.